Fig. 1 · Structure
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PknB-IN-1
PknB Inhibitor
PknB-IN-1 is a selective inhibitor of protein kinase B (PknB), exhibiting an IC50 of 14.4 μM. This compound demonstrates significant anti-mycobacterial activity, effectively inhibiting the growth of M. tuberculosis H37Rv strain with a minimum inhibitory concentration (MIC) of 6.2 μg/mL. PknB-IN-1 is a valuable tool for research focused on mycobacterial infections and the development of novel anti-tuberculosis therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1447917-39-6 |
| Applications | PknB Inhibitor |
| Formula | C25H30N2O2 |
| Molecular Weight | 390.52 |
| SMILES | CCCCN(CC(CN1C=C(C2=C1C=CC=C2)/C=C/C(C3=CC=CC=C3)=O)O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.