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Biological Activity
Plecanatide acetate is a guanylate cyclase-C (GC-C) receptor agonist, with an EC50 of 190 nM in T84 cells. Plecanatide acetate shows anti-inflammatory activity in models of murine colitis.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 5.74 mL | 28.7 mL | 57.41 mL |
| 0.5 mM | 1.15 mL | 5.74 mL | 11.48 mL |
| 1 mM | 0.57 mL | 2.87 mL | 5.74 mL |
| 5 mM | 0.11 mL | 0.57 mL | 1.15 mL |
*The above data is based on the productmolecular weight 1741.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21393 |
|---|---|
| Actions | Agonist |
| CAS No. | 1075732-84-1 |
| Formula | C67H108N18O28S4 |
| M. Wt | 1741.94 |
| Purity | >98% |
| SMILES | OC(C)=O.[NDECELCVNV ACTGCL] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Contact information
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