Fig. 1 · Structure

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PptT-IN-2

PptT Inhibitor

PptT-IN-2 is a potent inhibitor of phosphopantetheinyl transferase (PptT), exhibiting an IC50 value of 2.5 μM. PptT is a critical enzyme involved in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. This compound is valuable for research into tuberculosis, particularly in studies focusing on the therapeutic modulation of lipid biosynthesis and virulence factor expression.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3035894-73-3
Applications PptT Inhibitor
Formula C22H29N5O2
Molecular Weight 395.50
SMILES
CCNC(NC(NC1=C(C=C(C=C1CC)C(NCC2=CC=CC=C2)=O)CC)=O)=N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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