Fig. 1 · Structure

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PqsR-IN-1

PqsR Inhibitor

PqsR-IN-1 is a selective inhibitor of PqsR, a crucial quorum sensing transcriptional regulator in Pseudomonas aeruginosa. This compound effectively reduces pyocyanin production, an important virulence factor associated with infection severity. Its low cytotoxicity makes PqsR-IN-1 suitable for investigating quorum sensing mechanisms and developing therapeutic strategies against bacterial infections.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2982271-62-3
Applications PqsR Inhibitor
Formula C17H18ClN3OS
Molecular Weight 347.86
SMILES
CCCCCC1=NC(CN2C=NC3=CC=C(C=C3C2=O)Cl)=CS1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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