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PqsR-IN-2

PqsR Inhibitor

PqsR-IN-2 is a potent inhibitor of the PqsR protein, a quorum sensing transcriptional regulator in Pseudomonas aeruginosa. This compound effectively attenuates the production of pyocyanin, a virulence factor associated with bacterial pathogenicity, while demonstrating low cytotoxicity. PqsR-IN-2 is suitable for research applications focused on understanding quorum sensing mechanisms and developing therapeutic strategies against Pseudomonas aeruginosa infections.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2982271-63-4
Applications	PqsR Inhibitor
Formula	C₁₈H₂₀ClN₃OS
Molecular Weight	361.89
SMILES	CCCCCCC1=NC(CN2C=NC3=CC=C(C=C3C2=O)Cl)=CS1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.