Fig. 1 · Structure
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PqsR/LasR-IN-1
PqsR/LasR Inhibitor
PqsR/LasR-IN-1 is a potent inhibitor of the PqsR and LasR signaling systems in Pseudomonas aeruginosa. This compound exhibits significant anti-virulence properties by effectively reducing the production of critical factors such as biofilm, pyocyanin, and rhamnolipids. PqsR/LasR-IN-1 is valuable for research applications focused on quorum sensing and the development of novel therapeutic strategies against bacterial infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 924818-33-7 |
| Applications | PqsR/LasR Inhibitor |
| Formula | C24H20ClNO3 |
| Molecular Weight | 405.87 |
| SMILES | CC1=C(C=C(C=C1)NC(C2=CC3=C(C(OC(C3)C4=CC=C(C=C4)Cl)=O)C=C2)=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.