Pramipexole-d5 dihydrochloride is a deuterated form of Pramipexole dihydrochloride, a selective agonist of the dopamine D2-type receptor that effectively crosses the blood-brain barrier. With binding affinities (Kis) of 2.2 nM for D2-type receptors, alongside 3.9 nM, 0.5 nM, and 1.3 nM for D2, D3, and D4 receptors respectively, it serves as a valuable tool in research. This reagent is primarily utilized in studies related to Parkinson's disease and restless legs syndrome, facilitating analysis of dopaminergic pathways and receptor interactions.
Pramipexole-d5 dihydrochloride is a deuterated form of Pramipexole dihydrochloride, a selective agonist of the dopamine D2-type receptor that effectively crosses the blood-brain barrier. With binding affinities (Kis) of 2.2 nM for D2-type receptors, alongside 3.9 nM, 0.5 nM, and 1.3 nM for D2, D3, and D4 receptors respectively, it serves as a valuable tool in research. This reagent is primarily utilized in studies related to Parkinson's disease and restless legs syndrome, facilitating analysis of dopaminergic pathways and receptor interactions.
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