PRMT5-IN-17

Catalog No.: A26635
PRMT5 Inhibitor
PRMT5-IN-17 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), a key enzyme involved in epigenetic regulation. This compound demonstrates significant anti-tumor activity, making it a promising candidate for cancer research. PRMT5's role in modulating gene expression through arginine methylation highlights the relevance of PRMT5-IN-17 in studies aimed at understanding cancer progression and developing novel therapeutic strategies.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPRMT5-IN-17 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), a key enzyme involved in epigenetic regulation. This compound demonstrates significant anti-tumor activity, making it a promising candidate for cancer research. PRMT5's role in modulating gene expression through arginine methylation highlights the relevance of PRMT5-IN-17 in studies aimed at understanding cancer progression and developing novel therapeutic strategies.
Product Information
Catalog NumA26635
FormulaC26H33N7O2
Molecular Weight475.59
CAS Number2755304-03-9
SMILESCC(N1CCC(NC2=C3C(C(NC[C@@H](O)CN4CC5=C(C=CC=C5)CC4)=NC=C3)=NC=N2)CC1)=O
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