PRMT5-IN-44

Catalog No.: A26674
PRMT5 Inhibitor
PRMT5-IN-44 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5). This compound exhibits significant anti-proliferative effects in various cancer cell lines, making it a valuable tool for studying the role of PRMT5 in tumorigenesis. PRMT5-IN-44 is particularly relevant for research applications focused on cancer biology and therapeutic development targeting PRMT5-mediated pathways.
Grouped product items
Size Price Stock Qty
25mg
$1,780.00
In stock
50mg
$2,280.00
In stock
100mg
$2,960.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPRMT5-IN-44 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5). This compound exhibits significant anti-proliferative effects in various cancer cell lines, making it a valuable tool for studying the role of PRMT5 in tumorigenesis. PRMT5-IN-44 is particularly relevant for research applications focused on cancer biology and therapeutic development targeting PRMT5-mediated pathways.
Product Information
Catalog NumA26674
FormulaC23H19F4N5O2
Molecular Weight473.42
CAS Number3034746-35-2
SMILESO=C(N1[C@@H](C2=CC=C(C=C2)C(F)(F)F)COC[C@H]1C)C3=C(F)C=C4N=C(N)C5=CN=CN5C4=C3
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