PROTAC WDR5 degrader 1 is a bifunctional degrader that selectively targets WDR5, promoting its proteasomal degradation via a VHL-type E3 ligase mechanism. This compound consists of a WDR5 ligand, a VHL ligand, and a PROTAC linker, facilitating the targeted degradation of WDR5 in cellular environments. Its distinct mechanism of action makes it a valuable tool for investigating WDR5-related biological pathways and their involvement in various diseases, including cancer and developmental disorders. Researchers can utilize this reagent for studies in targeted protein degradation and gene regulation.
PROTAC WDR5 degrader 1 is a bifunctional degrader that selectively targets WDR5, promoting its proteasomal degradation via a VHL-type E3 ligase mechanism. This compound consists of a WDR5 ligand, a VHL ligand, and a PROTAC linker, facilitating the targeted degradation of WDR5 in cellular environments. Its distinct mechanism of action makes it a valuable tool for investigating WDR5-related biological pathways and their involvement in various diseases, including cancer and developmental disorders. Researchers can utilize this reagent for studies in targeted protein degradation and gene regulation.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
