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PRT062070 is a novel, oral, dual spleen tyrosine kinase (Syk) and janus kinase (JAK) inhibitor. Cerdulatinib preferentially inhibited JAK1 and JAK3 dependent cytokine mediated signaling and functional responses in various cell types.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.44 mL | 112.22 mL | 224.45 mL |
| 0.5 mM | 4.49 mL | 22.44 mL | 44.89 mL |
| 1 mM | 2.24 mL | 11.22 mL | 22.44 mL |
| 5 mM | 0.45 mL | 2.24 mL | 4.49 mL |
*The above data is based on the productmolecular weight 445.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14147 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 445.54 |
| Formula | C20H27N7O3S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1198300-79-6 |
| Synonyms | Cerdulatinib,PRT2070,PRT-2070,PRT 2070,PRT-062070,PRT062070 |
| SMILES | CCS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4CC4)C(=O)N |
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