PRT 062070 (Cerdulatinib)

Catalog No.: A14147

Dual Syk and JAK inhibitor

PRT 062070 (Cerdulatinib)

PRT 062070 (Cerdulatinib) Chemical Structure

CAS NO. 1198300-79-6

PRT062070 is a novel, oral, dual spleen tyrosine kinase (Syk) and janus kinase (JAK) inhibitor. Cerdulatinib preferentially inhibited JAK1 and JAK3 dependent cytokine mediated signaling and functional responses in various cell types.

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$250.00
50 mg
$400.00
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Biological Activity

PRT062070 is a novel, oral, dual spleen tyrosine kinase (Syk) and janus kinase (JAK) inhibitor. Cerdulatinib preferentially inhibited JAK1 and JAK3 dependent cytokine mediated signaling and functional responses in various cell types.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.44 mL 112.22 mL 224.45 mL
0.5 mM 4.49 mL 22.44 mL 44.89 mL
1 mM 2.24 mL 11.22 mL 22.44 mL
5 mM 0.45 mL 2.24 mL 4.49 mL

*The above data is based on the productmolecular weight 445.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14147
Actions Inhibitor
CAS No. 1198300-79-6
Formula C20H27N7O3S
M. Wt 445.54
Purity >98%
Synonyms Cerdulatinib,PRT2070,PRT-2070,PRT 2070,PRT-062070,PRT062070
SMILES CCS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4CC4)C(=O)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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