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PSB-06126

Catalog No.: A65351
NTPDase Inhibitor
PSB-06126 is a selective inhibitor of nucleoside triphosphate diphosphohydrolase (NTPDase), demonstrating Ki values of 0.33 μM for rat NTPDase 1, 19.1 μM for NTPDase 2, and 2.22 μM for NTPDase 3. In human NTPDase 3, it exhibits an IC50 value of 7.76 μM and a Ki value of 4.39 μM. This compound is useful for studying the role of NTPDases in purinergic signaling and may aid in the exploration of therapeutic strategies targeting related pathological conditions.
PSB-06126 1052089-16-3 NTPDase Inhibitor
Grouped product items
Size Price Stock Qty
1mg
$30.00
In stock
5mg
$65.00
In stock
10mg
$110.00
In stock
25mg
$185.00
In stock
50mg
$265.00
In stock
100mg
$385.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPSB-06126 is a selective inhibitor of nucleoside triphosphate diphosphohydrolase (NTPDase), demonstrating Ki values of 0.33 μM for rat NTPDase 1, 19.1 μM for NTPDase 2, and 2.22 μM for NTPDase 3. In human NTPDase 3, it exhibits an IC50 value of 7.76 μM and a Ki value of 4.39 μM. This compound is useful for studying the role of NTPDases in purinergic signaling and may aid in the exploration of therapeutic strategies targeting related pathological conditions.
Product Information
Catalog NumA65351
FormulaC24H15N2NaO5S
Molecular Weight466.44
CAS Number1052089-16-3
SMILESO=S(C(C(N)=C1C2=O)=CC(NC3=C4C=CC=CC4=CC=C3)=C1C(C5=C2C=CC=C5)=O)(O[Na])=O
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Immunology & Inflammation > NTPDase