h-NTPDase-IN-3 is a potent pan-inhibitor of NTPDase enzymes, demonstrating varying inhibitory activity with IC50 values of 34.13 μM for h-NTPDase1, 0.33 μM for h-NTPDase2, 23.21 μM for h-NTPDase3, and 2.48 μM for h-NTPDase8. This compound is valuable for research focused on purinergic signaling, offering insights into the regulation of extracellular nucleotide levels. Its ability to inhibit multiple NTPDase isoforms makes it suitable for studies exploring their roles in various physiological and pathological processes.
h-NTPDase-IN-3 is a potent pan-inhibitor of NTPDase enzymes, demonstrating varying inhibitory activity with IC50 values of 34.13 μM for h-NTPDase1, 0.33 μM for h-NTPDase2, 23.21 μM for h-NTPDase3, and 2.48 μM for h-NTPDase8. This compound is valuable for research focused on purinergic signaling, offering insights into the regulation of extracellular nucleotide levels. Its ability to inhibit multiple NTPDase isoforms makes it suitable for studies exploring their roles in various physiological and pathological processes.
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