PSC-833 (Valspodar)

Catalog No.: A11080

MDR1/P-gp Inhibitor

PSC-833 (Valspodar)

PSC-833 (Valspodar) Chemical Structure

CAS NO. 121584-18-7

PSC-833 is a kind of P-glycoprotein (P-gp) modulator that inhibits P-gp-mediated multidrug-resistance (MDR).

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Package Price Qty
2 mg
$100.00
5 mg
$200.00
10 mg
$350.00
25 mg
$620.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Somin Lee, .et al. 3D brain angiogenesis model to reconstitute functional human blood-brain barrier in vitro, ?Biotechnol Bioeng, 2019, 10 November
  • Somin Lee, .et al. 3D brain angiogenesis model to reconstitute maturation of functional human blood-brain barrier in vitro, bioRxiv, 2018, Nov. 18
  • Watanabe N, .et al. The possible clinical impact of risperidone on P-glycoprotein-mediated transport of tacrolimus: A case report and in vitro study, Biopharm Drug Dispos, 2018, Jan;39(1):30-37 PMID: 29055041
  • Higashi H, .et al. In Vitro P-Glycoprotein-Mediated Transport of Tadalafil: A Comparison with Sildenafil, Biol Pharm Bull, 2017, 40(8):1314-1319 PMID: 28769012

Biological Activity

PSC-833 is a kind of P-glycoprotein (P-gp) modulator that inhibits P-gp-mediated multidrug-resistance (MDR).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 8.23 mL 41.17 mL 82.33 mL
0.5 mM 1.65 mL 8.23 mL 16.47 mL
1 mM 0.82 mL 4.12 mL 8.23 mL
5 mM 0.16 mL 0.82 mL 1.65 mL

*The above data is based on the productmolecular weight 1214.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11080
Actions Inhibitor
M. Wt 1214.6
Formula C63H111N11O12
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 121584-18-7
Synonyms Valspodar, PSC833, Amdray
SMILES C/C=C/C[[email protected]@H](C)C(=O)[[email protected]]1C(=O)N[[email protected]](C(=O)N(CC(=O)N([[email protected]](C(=O)N[[email protected]](C(=O)N([[email protected]](C(=O)N[[email protected]](C(=O)N[[email protected]@H](C(=O)N([[email protected]](C(=O)N([[email protected]](C(=O)N([[email protected]](C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)C(C)C

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