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- Somin Lee,et al. 3D brain angiogenesis model to reconstitute maturation of functional human blood-brain barrier in vitro, bioRxiv, 2018, Nov. 18
- Watanabe N,et al. The possible clinical impact of risperidone on P-glycoprotein-mediated transport of tacrolimus: A case report and in vitro study, Biopharm Drug Dispos, 2018, Jan;39(1):30-37 29055041
- Higashi H,et al. In Vitro P-Glycoprotein-Mediated Transport of Tadalafil: A Comparison with Sildenafil, Biol Pharm Bull, 2017, 40(8):1314-1319 28769012
|Storage||at -20°C 3 years Powder|
|Synonyms||Valspodar, PSC833, Amdray|
|SMILES code||C/C=C/C[[email protected]@H](C)C(=O)[[email protected]]1C(=O)N[[email protected]](C(=O)N(CC(=O)N([[email protected]](C(=O)N[[email protected]](C(=O)N([[email protected]](C(=O)N[[email protected]](C(=O)N[[email protected]@H](C(=O)N([[email protected]](C(=O)N([[email protected]](C(=O)N([[email protected]](C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)C(C)C|
|Chemical Name||6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-cyclosporin A|
|PSC-833 is a kind of P-glycoprotein (P-gp) modulator that inhibits P-gp-mediated multidrug-resistance (MDR).|
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||8.23 mL||41.17 mL||82.33mL|
|0.5 mM||1.65 mL||8.23 mL||16.47 mL|
|1 mM||0.82 mL||4.12 mL||8.23 mL|
|5 mM||0.16 mL||0.82 mL||1.65 mL|
*The above data is based on the productmolecular weight 1214.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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