PTDA-PEG4-azide is a cleavable 4 unit polyethylene glycol (PEG) linker designed for the construction of antibody-drug conjugates (ADCs). This linker contains an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, PTDA-PEG4-azide can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules featuring DBCO or BCN groups, making it a versatile tool in chemical biology and drug development applications.
PTDA-PEG4-azide is a cleavable 4 unit polyethylene glycol (PEG) linker designed for the construction of antibody-drug conjugates (ADCs). This linker contains an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, PTDA-PEG4-azide can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules featuring DBCO or BCN groups, making it a versatile tool in chemical biology and drug development applications.
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