Fig. 1 · Structure

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PXYC12

RpsA Antagonist

PXYC12 is an antagonist of ribosomal protein S1 (RpsA) with dissociation constants (Kd) of 2.67 and 4.67 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA is crucial in the trans-translation mechanism of Mycobacterium tuberculosis, making PXYC12 a valuable tool for studying bacterial protein synthesis and exploring potential therapeutic strategies against tuberculosis. This compound is ideal for research applications focusing on antimicrobial drug discovery and the modulation of ribosomal function.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 1112415-91-4
Applications RpsA Antagonist
Formula C15H15N5O2S
Molecular Weight 329.38
SMILES
CC1=CC(CNC(CSC2=NC3=C(C(N2)=O)NC=N3)=O)=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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