Fig. 1 · Structure
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PXYC13
RpsA Antagonist
PXYC13 is an antagonist of ribosomal protein S1 (RpsA), exhibiting dissociation constants (Kd) of 7.61 μM and 8.50 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. This compound is a valuable tool for investigations into the trans-translation mechanism in Mycobacterium tuberculosis. Its ability to inhibit RpsA makes it relevant for research into the pathogen’s protein synthesis processes and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1031940-69-8 |
| Applications | RpsA Antagonist |
| Formula | C15H15N5O2S |
| Molecular Weight | 329.38 |
| SMILES | CC1=CC=C(C=C1)CNC(CSC2=NC3=C(C(N2)=O)NC=N3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.