Fig. 1 · Structure
Documents & Downloads
PXYD3
RpsA Antagonist
PXYD3 is an antagonist of ribosomal protein S1 (RpsA), exhibiting dissociation constants (Kds) of 5.66 μM and 6.91 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA is crucial for the trans-translation process in Mycobacterium tuberculosis, making PXYD3 a valuable tool for researching antibiotic mechanisms and developing potential therapeutic agents against this pathogen. This compound facilitates studies on ribosomal function and interactions, contributing to the understanding of bacterial resistance mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2680554-46-3 |
| Applications | RpsA Antagonist |
| Formula | C25H21NO5 |
| Molecular Weight | 415.44 |
| SMILES | CC1=CC=CC(CNC(COC2=CC3=C(C(O)=C2)C(C=C(O3)C4=CC=CC=C4)=O)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.