Fig. 1 · Structure
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PXYD4
RpsA Antagonist
PXYD4 is an antagonist of ribosomal protein S1 (RpsA), exhibiting dissociation constants (Kd) of 3.24 μM and 1.64 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. It is relevant for studies involving the trans-translation mechanism in Mycobacterium tuberculosis (Mtb), making it a valuable tool for exploring potential therapeutic strategies against this pathogen. PXYD4's ability to inhibit RpsA may contribute to our understanding of bacterial protein synthesis and its implications in antibiotic resistance.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2712534-78-4 |
| Applications | RpsA Antagonist |
| Formula | C25H21NO5 |
| Molecular Weight | 415.44 |
| SMILES | CC1=CC=C(C=C1)CNC(COC2=CC3=C(C(O)=C2)C(C=C(O3)C4=CC=CC=C4)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.