(R)-ADX-47273

Catalog No.: A21887

mGluR5 positive allosteric modulator

(R)-ADX-47273

(R)-ADX-47273 Chemical Structure

CAS NO. 851881-59-9

(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation .

Availability: In stock

Package Price Qty
5 mg
$126.00
10 mg
$217.00
50 mg
$644.00
100 mg
$1,288.00
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Biological Activity

(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation .
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.07 mL 135.37 mL 270.74 mL
0.5 mM 5.41 mL 27.07 mL 54.15 mL
1 mM 2.71 mL 13.54 mL 27.07 mL
5 mM 0.54 mL 2.71 mL 5.41 mL

*The above data is based on the productmolecular weight 369.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21887
Actions Modulator
CAS No. 851881-59-9
Formula C20H17F2N3O2
M. Wt 369.36
Purity >98%
Synonyms BX 471, BX-471
SMILES O=C(N1C[[email protected]](C2=NC(C3=CC=C(C=C3)F)=NO2)CCC1)C4=CC=C(C=C4)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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