UNC2399

Catalog No.: A26790
Histone Methyltransferase Inhibitor
UNC2399, a selective inhibitor of the histone methyltransferase EZH2, exhibits high in vitro potency with an IC50 of 17 nM. This biotinylated compound facilitates the study of EZH2-mediated pathways by enabling researchers to probe histone methylation dynamics. UNC2399 is valuable for investigations into cancer biology, epigenetics, and therapeutic development targeting methyltransferases.
Grouped product items
Size Price Stock Qty
5mg
$390.00
In stock
10mg
$765.00
In stock
25mg
$1,555.00
In stock
50mg
$2,425.00
In stock
100mg
$3,775.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionUNC2399, a selective inhibitor of the histone methyltransferase EZH2, exhibits high in vitro potency with an IC50 of 17 nM. This biotinylated compound facilitates the study of EZH2-mediated pathways by enabling researchers to probe histone methylation dynamics. UNC2399 is valuable for investigations into cancer biology, epigenetics, and therapeutic development targeting methyltransferases.
Product Information
Catalog NumA26790
FormulaC67H104N10O17S
Molecular Weight1353.66
CAS Number2412791-72-9
SMILESCCCC(C=C(NC1=O)C)=C1CNC(C2=C3C(N(N=C3)C(C)C)=CC(C4=CN=C(N5CCN(CC5)C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCC[C@H]6[C@]7([H])[C@](NC(N7)=O)([H])CS6)=O)=O)C=C4)=C2)=O
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