(-)-JQ1

Catalog No.: A14160

BET bromodomain inhibitor

(-)-JQ1

(-)-JQ1 Chemical Structure

CAS NO. 1268524-71-5

The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $70.00

Special Price $56.00

10 mg

Regular Price: $90.00

Special Price $72.00

25 mg

Regular Price: $150.00

Special Price $120.00

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Biological Activity

The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.88 mL 109.41 mL 218.82 mL
0.5 mM 4.38 mL 21.88 mL 43.76 mL
1 mM 2.19 mL 10.94 mL 21.88 mL
5 mM 0.44 mL 2.19 mL 4.38 mL

*The above data is based on the productmolecular weight 457. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14160
Actions Inhibitor
CAS No. 1268524-71-5
Formula C23H25ClN4O2S
M. Wt 457
Purity >98%
SMILES CC1=C(SC2=C1C(=N[[email protected]@H](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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