Biological Activity
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.88 mL | 109.41 mL | 218.82 mL |
0.5 mM | 4.38 mL | 21.88 mL | 43.76 mL |
1 mM | 2.19 mL | 10.94 mL | 21.88 mL |
5 mM | 0.44 mL | 2.19 mL | 4.38 mL |
*The above data is based on the productmolecular weight 457. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A14160 |
---|---|
Actions | Inhibitor |
CAS No. | 1268524-71-5 |
Formula | C23H25ClN4O2S |
M. Wt | 457 |
Purity | >98% |
SMILES | CC1=C(SC2=C1C(=N[[email protected]@H](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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