Fig. 1 · Structure

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(R)-ZG197

SaClpP Activator

(R)-ZG197 is a selective activator of Staphylococcus aureus caseinolytic protease P (SaClpP), demonstrating an EC50 of 1.5 μM. Additionally, it activates Homo sapiens ClpP (HsClpP) with an EC50 of 31.4 μM. This compound is valuable for studying protease regulation and has potential applications in understanding bacterial protein degradation pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Activator
CAS Number 2999672-72-7
Applications SaClpP Activator
Formula C28H35F3N4O3
Molecular Weight 532.60
SMILES
O=C(N1CCC(N([C@H]2[C@@H](C)CC)[C@]1([H])CN([C@H](C)C3=C(C=CC=C4)C4=CC=C3)C2=O)=O)NCCCC(F)(F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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