(Rac)-SAG is a potent agonist of the Smoothened (Smo) receptor, exhibiting an EC50 of 3 nM and a Kd of 59 nM. This compound activates the Hedgehog signaling pathway, making it an invaluable tool in studies focused on Smo-mediated processes. Additionally, (Rac)-SAG can counteract the inhibition of Smo by Cyclopamine, facilitating research into signaling and developmental biology.
(Rac)-SAG is a potent agonist of the Smoothened (Smo) receptor, exhibiting an EC50 of 3 nM and a Kd of 59 nM. This compound activates the Hedgehog signaling pathway, making it an invaluable tool in studies focused on Smo-mediated processes. Additionally, (Rac)-SAG can counteract the inhibition of Smo by Cyclopamine, facilitating research into signaling and developmental biology.
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