Ramelteon-d3

Catalog No.: A61736
Stable Isotope
Ramelteon-d3 is a deuterium-labeled derivative of Ramelteon, a highly selective and orally active agonist of melatonin receptors MT1 and MT2, exhibiting Ki values of 14 pM and 112 pM, respectively. This stable isotope is utilized in pharmacokinetic studies and research applications focused on insomnia, providing insight into sleep modulation mechanisms. Ramelteon is known for its efficacy in reducing sleep onset without causing residual effects, rebound insomnia, or withdrawal symptoms with long-term use.
Grouped product items
Size Price Stock Qty
1mg
$255.00
In stock
5mg
$805.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRamelteon-d3 is a deuterium-labeled derivative of Ramelteon, a highly selective and orally active agonist of melatonin receptors MT1 and MT2, exhibiting Ki values of 14 pM and 112 pM, respectively. This stable isotope is utilized in pharmacokinetic studies and research applications focused on insomnia, providing insight into sleep modulation mechanisms. Ramelteon is known for its efficacy in reducing sleep onset without causing residual effects, rebound insomnia, or withdrawal symptoms with long-term use.
Product Information
Catalog NumA61736
FormulaC16H18D3NO2
Molecular Weight262.36
CAS Number1432057-38-9
SMILES[2H]C([2H])([2H])CC(NCC[C@H]1C2=C(CC1)C=CC3=C2CCO3)=O
SynonymsTAK-375-d3
Useful Calculator

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