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Rbin-1

Catalog No.: A16682

Eukaryotic ribosome biogenesis inhibitor

Rbin-1

Rbin-1 Chemical Structure

CAS NO. 328023-11-6

Rbin-1 is a potent, reversible, and specific chemical inhibitor of eukaryotic ribosome biogenesis. Rbin-1 inhibits the ATPase with GI50 of 136 nM. Rbin-1 is a potent and selective chemical inhibitor of Midasin (Mdn1).

Availability: In stock

Package Price Qty
1 mg
$99.00
5 mg
$297.00
10 mg
$506.00
50 mg
$1,518.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Rbin-1 is a potent, reversible, and specific chemical inhibitor of eukaryotic ribosome biogenesis. Rbin-1 inhibits the ATPase with GI50 of 136 nM. Rbin-1 is a potent and selective chemical inhibitor of Midasin (Mdn1).
In vitro DMSO 20 mg/mL (78.02 mM)
Water Insoluble
Ethanol <1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 39.01 mL 195.06 mL 390.12 mL
0.5 mM 7.8 mL 39.01 mL 78.02 mL
1 mM 3.9 mL 19.51 mL 39.01 mL
5 mM 0.78 mL 3.9 mL 7.8 mL

*The above data is based on the productmolecular weight 256.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16682
Actions Inhibitor
CAS No. 328023-11-6
Formula C13H12N4S
M. Wt 256.33
Purity >98%
Synonyms Ribozinoindole-1
SMILES C=C(C)CSC1=NN=C2C(NC3=C2C=CC=C3)=N1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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