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RCB18350

Anti-Tuberculosis Agent

RCB18350 is an isoxazole derivative that serves as a potent anti-tuberculosis agent. It exhibits significant bacteriostatic activity against Mycobacterium tuberculosis, demonstrating an MIC of 1.25 μg/mL. RCB18350 is effective against multidrug-resistant strains, including clinical isolates of MDR-TB, as well as slow-growing mycobacteria such as Mycobacterium bovis BCG and Mycobacterium avium, making it valuable for research in tuberculosis treatment and resistance mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3052630-27-7
Applications	Anti-Tuberculosis Agent
Formula	C₁₉H₁₈F₃N₃O₄S
Molecular Weight	441.42
SMILES	CCOC(C1=NOC(CCCSC2=CC=C(C3=NOC(C(F)(F)F)=N3)C=C2C)=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.