Risperidone-d4 is a deuterated analog of Risperidone, functioning primarily as a serotonin 5-HT2 receptor antagonist and dopamine D2 receptor antagonist. It is characterized by its inhibitory effects on P-Glycoprotein, with binding affinities (Kis) of 4.8 nM for the 5-HT2A receptor and 5.9 nM for the dopamine D2 receptor. This stable isotope is valuable for pharmacokinetic studies, metabolic profiling, and tracing mechanisms in neurological research applications.
Risperidone-d4 is a deuterated analog of Risperidone, functioning primarily as a serotonin 5-HT2 receptor antagonist and dopamine D2 receptor antagonist. It is characterized by its inhibitory effects on P-Glycoprotein, with binding affinities (Kis) of 4.8 nM for the 5-HT2A receptor and 5.9 nM for the dopamine D2 receptor. This stable isotope is valuable for pharmacokinetic studies, metabolic profiling, and tracing mechanisms in neurological research applications.
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