Risperidone E-oxime is a recognized impurity of Risperidone, primarily targeting serotonin 5-HT2 receptors and dopamine D2 receptors. This compound acts as a serotonin 5-HT2 receptor blocker and a potent dopamine D2 receptor antagonist, exhibiting inhibition constants (Kis) of 4.8 nM and 5.9 nM, respectively. It is particularly relevant for studies involving antipsychotic drug development, pharmacokinetics, and the assessment of metabolite profiles.
Risperidone E-oxime is a recognized impurity of Risperidone, primarily targeting serotonin 5-HT2 receptors and dopamine D2 receptors. This compound acts as a serotonin 5-HT2 receptor blocker and a potent dopamine D2 receptor antagonist, exhibiting inhibition constants (Kis) of 4.8 nM and 5.9 nM, respectively. It is particularly relevant for studies involving antipsychotic drug development, pharmacokinetics, and the assessment of metabolite profiles.
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