RJW103 is an acid-stable agonist of SF-1 (NR5A1) and LRH-1, demonstrating pEC50 values of 6.5 and 5.9, respectively. This compound effectively activates SF-1- and LRH-1-mediated transcription of endogenous target genes. Research applications include investigations in cancer biology, endocrinology, and metabolic diseases, particularly in the context of adrenocortical tumors.
RJW103 is an acid-stable agonist of SF-1 (NR5A1) and LRH-1, demonstrating pEC50 values of 6.5 and 5.9, respectively. This compound effectively activates SF-1- and LRH-1-mediated transcription of endogenous target genes. Research applications include investigations in cancer biology, endocrinology, and metabolic diseases, particularly in the context of adrenocortical tumors.
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