Fig. 1 · Structure
Documents & Downloads
Ro 14-9578
Bacteriostatic Agent
Ro 14-9578 is a tricyclic quinolone analog that serves as a bacteriostatic agent by inhibiting DNA biosynthesis and supercoiling in Escherichia coli, with IC50 values of 117 μM and 66.8 μM, respectively. This compound demonstrates significant antibacterial activity against a range of Gram-negative bacteria as well as Staphylococcus aureus. Its capacity to disrupt bacterial DNA processes makes Ro 14-9578 a valuable tool for research into antimicrobial mechanisms and the development of new antibacterial therapies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 100891-41-6 |
| Applications | Bacteriostatic Agent |
| Formula | C16H13NO5 |
| Molecular Weight | 299.28 |
| SMILES | O=C(C1=CN2C(C3=C(CC2C)C=C4OCOC4=C3)=CC1=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.