Ropinirole-d4 hydrochloride

Catalog No.: A60167
Stable Isotope
Ropinirole-d4 hydrochloride is a deuterium-labeled derivative of Ropinirole hydrochloride, functioning primarily as a selective D2/D3 receptor agonist. It exhibits a Kiof of 29 nM for the D2 receptor and demonstrates pEC50 values of 7.4, 8.4, and 6.8 for human D2, D3, and D4 receptors, respectively. With its specific action and lack of affinity for D1 receptors, Ropinirole-d4 is particularly valuable in investigations related to Parkinson's disease and receptor pharmacology.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionRopinirole-d4 hydrochloride is a deuterium-labeled derivative of Ropinirole hydrochloride, functioning primarily as a selective D2/D3 receptor agonist. It exhibits a Kiof of 29 nM for the D2 receptor and demonstrates pEC50 values of 7.4, 8.4, and 6.8 for human D2, D3, and D4 receptors, respectively. With its specific action and lack of affinity for D1 receptors, Ropinirole-d4 is particularly valuable in investigations related to Parkinson's disease and receptor pharmacology.
Product Information
Catalog NumA60167
FormulaC16H21D4ClN2O
Molecular Weight300.86
CAS Number1330261-37-4
SMILESC(CN(C(CC)([2H])[2H])C(CC)([2H])[2H])C1=C2C(NC(=O)C2)=CC=C1.Cl
SynonymsSKF 101468-d4 hydrochloride
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