Rosiglitazone-d4 is a deuterated form of Rosiglitazone, a selective agonist of PPARγ with an EC50 of 60 nM and a Kd of 40 nM. In addition to its role as a PPARγ activator, Rosiglitazone also functions as a TRPC5 activator (EC50: 30 μM) and a TRPM3 inhibitor. This compound is valuable for research into obesity, diabetes, cellular senescence, and ovarian cancer. Its stable isotope labeling allows for precise tracking and quantification in various biological studies.
Rosiglitazone-d4 is a deuterated form of Rosiglitazone, a selective agonist of PPARγ with an EC50 of 60 nM and a Kd of 40 nM. In addition to its role as a PPARγ activator, Rosiglitazone also functions as a TRPC5 activator (EC50: 30 μM) and a TRPM3 inhibitor. This compound is valuable for research into obesity, diabetes, cellular senescence, and ovarian cancer. Its stable isotope labeling allows for precise tracking and quantification in various biological studies.
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