RSL3

Catalog No.: A15865
Ferroptosis inhibitor
RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.
Grouped product items
Size Price Stock Qty
1mg
$25.00
In stock
2mg
$40.00
In stock
5mg
$65.00
In stock
10mg
$120.00
In stock
25mg
$235.00
In stock
50mg
$360.00
In stock
100mg
$475.00
In stock
500mg
$1,075.00
In stock
1g
$1,425.00
In stock
10mM * 1mL in DMSO
$60.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's RSL3 has been cited by 7 publications
  • Naoya Yamada, .et al. , Nat Commun, 2024, 15:2195
  • Ning Li, .et al. , J Ovarian Res, 2024, Feb 23;17(1):49 PMID: 38396022
  • Yuki Kojima, .et al. , Journal of Gastroenterology, 2023, Nov 10
  • Qingyu Zhang, .et al. , Cell Death Discov, 2023, Mar 8;9(1):83 PMID: 36882396
  • Sampilvanjil A, .et al. , Am J Physiol Heart Circ Physiol, 2020, Mar 1;318(3):H508-H518 PMID: 31975626
  • Fujiki K, .et al. , Cell Death Differ, 2019, Feb 25 PMID: 30804470
  • Samantha W. Alvarez, .et al. , Nature, 2017, Nov 30; 551(7682): 639-643 PMID: 29168506
  • Biological Activity
    Discription RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A15865
    Formula C23H21ClN2O5
    Molecular Weight 440.88
    CAS Number 1219810-16-8
    SMILES COC(C1=CC=C([C@@]2([H])C3=C(C4=CC=CC=C4N3)C[C@](N2C(CCl)=O)([H])C(OC)=O)C=C1)=O
    Synonyms 1S,3R-RSL3
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 82 mg/mL (185.99 mM)
    Water Insoluble
    Ethanol 20 mg/mL
    In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.68 mL 113.41 mL 226.82 mL
    0.5 mM 4.54 mL 22.68 mL 45.36 mL
    1 mM 2.27 mL 11.34 mL 22.68 mL
    5 mM 0.45 mL 2.27 mL 4.54 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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