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Brevinin-1Ea

Catalog No.: A49218
Antimicrobial Peptide
Brevinin-1Ea is an antimicrobial peptide derived from the skin secretions of the European green frog, Rana esculenta. This peptide exhibits broad-spectrum antimicrobial activity against various bacteria and fungi, making it a valuable tool in studies related to innate immunity and host defense mechanisms. Its unique properties allow researchers to explore potential applications in developing novel antimicrobial agents and enhancing skin protection strategies.
Brevinin-1Ea 156793-64-5 Antimicrobial Peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBrevinin-1Ea is an antimicrobial peptide derived from the skin secretions of the European green frog, Rana esculenta. This peptide exhibits broad-spectrum antimicrobial activity against various bacteria and fungi, making it a valuable tool in studies related to innate immunity and host defense mechanisms. Its unique properties allow researchers to explore potential applications in developing novel antimicrobial agents and enhancing skin protection strategies.
Product Information
Catalog NumA49218
FormulaC123H206N30O28S3
Molecular Weight2649.33
CAS Number156793-64-5
SequencePhe-Leu-Pro-Ala-Ile-Phe-Arg-Met-Ala-Ala-Lys-Val-Val-Pro-Thr-Ile-Ile-Cys-Ser-Ile-Thr-Lys-Lys-Cys (Disulfide bridge:Cys18-Cys24)
Sequence shorteningFLPAIFRMAAKVVPTIICSITKKC (Disulfide bridge:Cys18-Cys24)
SMILESC([C@@H](NC([C@H](CC1=CC=CC=C1)N)=O)CC(C)C)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]5C(=O)N[C@@H](CO)C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(O)=O)CSSC5)[H])[H])=O)[C@H](CC)C)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)CCC4)C(C)C)=O)[C@H](C)C)=O)CCCCN)=O)C)=O)C)=O)CCSC)=O)CCCNC(=N)N)=O)=O)[C@H](CC)C)=O)C)=O)CCC2
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