Biological Activity
S107 hydrochloride is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 40.69 mL | 203.44 mL | 406.88 mL |
0.5 mM | 8.14 mL | 40.69 mL | 81.38 mL |
1 mM | 4.07 mL | 20.34 mL | 40.69 mL |
5 mM | 0.81 mL | 4.07 mL | 8.14 mL |
*The above data is based on the productmolecular weight 245.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A21839 |
---|---|
CAS No. | 1357476-46-0 |
Formula | C11H16ClNOS |
M. Wt | 245.77 |
Purity | >98% |
Synonyms | S 107, S-107 |
SMILES | COC1=CC=C2SCCN(CC2=C1)C.Cl |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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