Fig. 1 · Structure
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S1R agonist 1 hydrochloride
S1R Agonist
S1R agonist 1 hydrochloride is a selective agonist of the sigma-1 receptor (S1R), demonstrating a binding affinity with a Ki of 0.93 nM for S1R and 72 nM for the sigma-2 receptor (S2R). This compound displays neuroprotective properties against reactive oxygen species (ROS) and NMDA-induced neurotoxicity. S1R agonist 1 hydrochloride is applicable in research focused on neurodegenerative conditions and the modulation of cellular stress responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 242487-82-7 |
| Applications | S1R Agonist |
| Formula | C20H26ClNO |
| Molecular Weight | 331.88 |
| SMILES | [H]Cl.C1(OCCN2CCC(CC2)CC3=CC=CC=C3)=CC=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.