S1R Agonist 1 is a selective sigma-1 receptor (S1R) agonist, demonstrating a binding affinity (Ki) of 0.93 nM for S1R and 72 nM for S2R. This compound exhibits neuroprotective effects against reactive oxygen species (ROS) and N-methyl-D-aspartate (NMDA)-induced neurotoxicity. It is useful in research applications aimed at understanding neurodegenerative diseases and neuroprotection mechanisms.
S1R Agonist 1 is a selective sigma-1 receptor (S1R) agonist, demonstrating a binding affinity (Ki) of 0.93 nM for S1R and 72 nM for S2R. This compound exhibits neuroprotective effects against reactive oxygen species (ROS) and N-methyl-D-aspartate (NMDA)-induced neurotoxicity. It is useful in research applications aimed at understanding neurodegenerative diseases and neuroprotection mechanisms.
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