SARS-CoV-2 Mpro-IN-6

Catalog No.: A53452
SARS-CoV-2 Mpro Inhibitor
SARS-CoV-2 Mpro-IN-6 is a selective, covalent, irreversible inhibitor of the SARS-CoV-2 main protease (Mpro), exhibiting an IC50 of 0.18 μM. This compound specifically targets Mpro without inhibiting key human cathepsins B, F, K, and L, or caspase 3. SARS-CoV-2 Mpro-IN-6 is suitable for research applications focused on understanding COVID-19 pathogenesis and developing therapeutic strategies against SARS-CoV-2.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSARS-CoV-2 Mpro-IN-6 is a selective, covalent, irreversible inhibitor of the SARS-CoV-2 main protease (Mpro), exhibiting an IC50 of 0.18 μM. This compound specifically targets Mpro without inhibiting key human cathepsins B, F, K, and L, or caspase 3. SARS-CoV-2 Mpro-IN-6 is suitable for research applications focused on understanding COVID-19 pathogenesis and developing therapeutic strategies against SARS-CoV-2.
Product Information
Catalog NumA53452
FormulaC18H18Cl3N3O2S
Molecular Weight446.78
CAS Number2768834-48-4
SMILESO=C([C@H]1N(C2=CC=C(Cl)C(Cl)=C2)CCN(C(CCl)=O)C1)NCC3=CC=CS3
Useful Calculator

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