Saxagliptin hydrate

Catalog No.: A16694

DPP4 inhibitor

Saxagliptin hydrate

Saxagliptin hydrate Chemical Structure

CAS NO. 945667-22-1

Saxagliptin H2O(BMS477118 H2O) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM and Ki of 1.3 nM.

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Biological Activity

Saxagliptin H2O(BMS477118 H2O) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM and Ki of 1.3 nM.
In vitro DMSO 59 mg/mL (176.95 mM)
Water 1 mg/mL (2.99 mM)
Ethanol 59 mg/mL (176.95 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.99 mL 149.96 mL 299.91 mL
0.5 mM 6 mL 29.99 mL 59.98 mL
1 mM 3 mL 15 mL 29.99 mL
5 mM 0.6 mL 3 mL 6 mL

*The above data is based on the productmolecular weight 333.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16694
Actions Inhibitor
CAS No. 945667-22-1
Formula C18H27N3O3
M. Wt 333.43
Purity >98%
Synonyms BMS-477118 hydrate
SMILES N[[email protected]@H]([[email protected]@]1(C[[email protected]]2C3)C[[email protected]@]3(O)C[[email protected]](C2)C1)C(N([[email protected]@H](C4)C#N)[[email protected]@H]5[[email protected]]4C5)=O.O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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