SB 243213 dihydrochloride is a selective and high-affinity antagonist of the 5-HT2C receptor, exhibiting a pKi of 9.37 and a pKb of 9.8 for the human 5-HT2C receptor. This compound displays over 100-fold selectivity for the 5-HT2C receptor relative to various neurotransmitter receptors, enzymes, and ion channels. SB 243213 dihydrochloride is noted for its improved anxiolytic profile and holds potential for therapeutic applications in schizophrenia and motor disorders.
SB 243213 dihydrochloride is a selective and high-affinity antagonist of the 5-HT2C receptor, exhibiting a pKi of 9.37 and a pKb of 9.8 for the human 5-HT2C receptor. This compound displays over 100-fold selectivity for the 5-HT2C receptor relative to various neurotransmitter receptors, enzymes, and ion channels. SB 243213 dihydrochloride is noted for its improved anxiolytic profile and holds potential for therapeutic applications in schizophrenia and motor disorders.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
