Target & Activity
| Target | Activity | Value |
|---|---|---|
| IKK2 | IC50 | 3μM-12μM |
| CDK2/CyclinA | IC50 | 61μM |
| AUR2 | IC50 | 71μM |
| PRAK | IC50 | 75μM |
| p38α | IC50 | >100μM |
| p38β | IC50 | >100μM |
| p38γ | IC50 | >100μM |
| p38δ | IC50 | >100μM |
| ERK2 | IC50 | >100μM |
| GSK-3 | IC50 | >100μM |
| NIM1 | IC50 | >100μM |
| Chk1 | IC50 | >100μM |
| PAK5 | IC50 | >100μM |
| PKA | IC50 | >100μM |
| PKCβ | IC50 | >100μM |
| Lyn | IC50 | >100μM |
| FGFR1 | IC50 | >100μM |
| EGFR | IC50 | >100μM |
| LCK | IC50 | >100μM |
| c-Abl | IC50 | >100μM |
| MSK | IC50 | 123μM |
| JNK1 | IC50 | >200μM |
| JNK2 | IC50 | >200μM |
| JNK3 | IC50 | >200μM |
| MK2 | IC50 | >200μM |
| MK3 | IC50 | >200μM |
| RSKB | IC50 | >200μM |
| MKK7 | IC50 | >200μM |
28 targets · Scroll to view more
Cellular Effect
| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| NIH3T3 | IC50 | 7.9 μM | Inhibition of TNFalpha-induced NFkappaB activation in mouse NIH-3T3 cells expressing NFkappaB (unknown origin) preincubated for 15 mins followed by TNFalpha addition measured after 6 hrs by luciferase reporter gene assay | [PMID: 27352042] |