Fig. 1 · Structure
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Scopolamine hydrobromide trihydrate
Muscarinic Antagonist
Scopolamine hydrobromide trihydrate is a potent muscarinic antagonist known for its ability to penetrate the blood-brain barrier. It competitively inhibits 5-HT3 receptors, exhibiting an IC50 of 2.09 μM. This compound is frequently utilized in research related to cognitive and memory impairments, as well as in studies of postoperative nausea, vomiting, and motion sickness. Additionally, Scopolamine hydrobromide trihydrate is relevant in investigating various nervous system disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 6533-68-2 |
| Applications | Muscarinic Antagonist |
| Formula | C17H28BrNO7 |
| Molecular Weight | 438.31 |
| Synonyms | Hyoscine hydrobromide trihydrate |
| SMILES | O=C([C@@H](C1=CC=CC=C1)CO)O[C@H]2C[C@H]3[C@@H]4O[C@@H]4[C@H](N3C)C2.[H]Br.[H]O[H].[H]O[H].[H]O[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.