Fig. 1 · Structure
Documents & Downloads
Scopolamine hydrochloride
Muscarinic Antagonist
Scopolamine hydrochloride is a high-affinity muscarinic antagonist known for its ability to penetrate the blood-brain barrier. This compound effectively inhibits 5-HT3 receptors, exhibiting an IC50 value of 2.09 μM. Scopolamine hydrochloride is utilized in research settings to explore cognitive and memory impairment in animal models, as well as applications related to the prevention of postoperative nausea and vomiting, motion sickness, and various disorders of the nervous system.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 55-16-3 |
| Applications | Muscarinic Antagonist |
| Formula | C17H22ClNO4 |
| Molecular Weight | 339.81 |
| Synonyms | (-)-Scopolamine hydrochloride; Hyoscine hydrochloride |
| SMILES | O=C([C@@H](C1=CC=CC=C1)CO)O[C@H]2C[C@H]3[C@@H]4O[C@@H]4[C@H](N3C)C2.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.