SD-06

Catalog No.: A11563

p38 MAPK inhibitor

SD-06

SD-06 Chemical Structure

CAS NO. 271576-80-8

SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po).

Availability: In stock

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5 mg
$135.00
10 mg
$200.00
50 mg
$585.00
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Biological Activity

SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.13 mL 125.67 mL 251.34 mL
0.5 mM 5.03 mL 25.13 mL 50.27 mL
1 mM 2.51 mL 12.57 mL 25.13 mL
5 mM 0.5 mL 2.51 mL 5.03 mL

*The above data is based on the productmolecular weight 397.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11563
Actions Inhibitor
M. Wt 397.87
Formula C20H20ClN5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 271576-80-8
Synonyms SD 06, SD06
SMILES C1CN(CCC1C2=C(C(=NN2)C3=CC=C(C=C3)Cl)C4=NC=NC=C4)C(=O)CO

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