SD-06

Catalog No.: A11563

p38 MAPK inhibitor

SD-06

SD-06 Chemical Structure

CAS NO. 271576-80-8

SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po).

Availability: In stock

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5 mg
$135.00
10 mg
$200.00
50 mg
$585.00
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Biological Activity

SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po).
In vitro DMSO 77 mg/mL (193.53 mM)
Water Insoluble
Ethanol 2 mg/mL (5.02 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.13 mL 125.67 mL 251.34 mL
0.5 mM 5.03 mL 25.13 mL 50.27 mL
1 mM 2.51 mL 12.57 mL 25.13 mL
5 mM 0.5 mL 2.51 mL 5.03 mL

*The above data is based on the productmolecular weight 397.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11563
Actions Inhibitor
CAS No. 271576-80-8
Formula C20H20ClN5O2
M. Wt 397.87
Purity >98%
Synonyms SD 06, SD06
SMILES C1CN(CCC1C2=C(C(=NN2)C3=CC=C(C=C3)Cl)C4=NC=NC=C4)C(=O)CO
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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