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p38 MAPK inhibitor

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Catalog No. A11563

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SD-06 5mg A11563-5
SD-06 10mg A11563-10
SD-06 50mg A11563-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po).


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Chemical Information

Catalog Num A11563
Actions Inhibitor
M. Wt 397.87
Formula C20H20ClN5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 271576-80-8
Synonyms SD 06, SD06

Biological Activity

SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.13 mL 125.67 mL 251.34mL
0.5 mM 5.03 mL 25.13 mL 50.27 mL
1 mM 2.51 mL 12.57 mL 25.13 mL
5 mM 0.5 mL 2.51 mL 5.03 mL

*The above data is based on the productmolecular weight 397.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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