SIK2/3-IN-2 is a potent inhibitor of salt-inducible kinases 2 and 3 (SIK2 and SIK3), with IC50 values of 65 nM and 14 nM, respectively. Additionally, it acts as a p21-activated protein kinase (PAK) 1 inhibitor with a Ki of 20.7 nM. This compound is valuable for investigating hyperproliferative diseases and cancer, particularly in studies related to Paclitaxel-resistant ovarian cancer.
SIK2/3-IN-2 is a potent inhibitor of salt-inducible kinases 2 and 3 (SIK2 and SIK3), with IC50 values of 65 nM and 14 nM, respectively. Additionally, it acts as a p21-activated protein kinase (PAK) 1 inhibitor with a Ki of 20.7 nM. This compound is valuable for investigating hyperproliferative diseases and cancer, particularly in studies related to Paclitaxel-resistant ovarian cancer.
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