Silvestrol aglycone

Catalog No.: A11575

Silvestrol aglycone

Silvestrol aglycone Chemical Structure

CAS NO. 960365-65-5

Silvestrol aglycone is a Silvestrol analogue, inhibits protein translation initiation in cancer cells, with EC50s of 10 and 200 nM for myc-LUC and tub-LUC luciferase reporter protein translation, respectively. Anti-cancer activity.

Availability: In stock

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1 mg

Regular Price: $585.00

Special Price $468.00

5 mg

Regular Price: $1,755.00

Special Price $1,404.00

10 mg

Regular Price: $2,990.00

Special Price $2,392.00

50 mg

Regular Price: $8,970.00

Special Price $7,176.00

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Biological Activity

Silvestrol aglycone is a Silvestrol analogue, inhibits protein translation initiation in cancer cells, with EC50s of 10 and 200 nM for myc-LUC and tub-LUC luciferase reporter protein translation, respectively. Anti-cancer activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.9 mL 104.5 mL 208.99 mL
0.5 mM 4.18 mL 20.9 mL 41.8 mL
1 mM 2.09 mL 10.45 mL 20.9 mL
5 mM 0.42 mL 2.09 mL 4.18 mL

*The above data is based on the productmolecular weight 478.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11575
CAS No. 960365-65-5
Formula C27H26O8
M. Wt 478.49
Purity >98%
SMILES O=C([[email protected]]([[email protected]]1C2=CC=CC=C2)[[email protected]@H](O)[[email protected]]3(O)[[email protected]@]1(C4=CC=C(OC)C=C4)OC5=CC(O)=CC(OC)=C35)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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