SIRT-IN-5 is a selective inhibitor of SIRT3, demonstrating an IC50 value of 2.88 μM. This compound has been shown to promote the differentiation of multiple myeloma cells, facilitating increased expression of differentiation antigens such as CD49e, as well as enhancement of human immunoglobulin light chains λ and κ. SIRT-IN-5 is a valuable tool in research focused on the modulation of cellular differentiation processes in hematological malignancies.
SIRT-IN-5 is a selective inhibitor of SIRT3, demonstrating an IC50 value of 2.88 μM. This compound has been shown to promote the differentiation of multiple myeloma cells, facilitating increased expression of differentiation antigens such as CD49e, as well as enhancement of human immunoglobulin light chains λ and κ. SIRT-IN-5 is a valuable tool in research focused on the modulation of cellular differentiation processes in hematological malignancies.
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