SIRT2-IN-14

Catalog No.: A57018
SIRT2 Inhibitor
SIRT2-IN-14 is a selective inhibitor of SIRT2, demonstrating an IC50 value of 0.196 μM. This compound effectively modulates SIRT2 activity, making it a valuable tool for studying the role of SIRT2 in various biological pathways. Research applications may include investigations into neurodegenerative diseases, cancer biology, and cellular metabolism, providing insights into the therapeutic potential of targeting SIRT2.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSIRT2-IN-14 is a selective inhibitor of SIRT2, demonstrating an IC50 value of 0.196 μM. This compound effectively modulates SIRT2 activity, making it a valuable tool for studying the role of SIRT2 in various biological pathways. Research applications may include investigations into neurodegenerative diseases, cancer biology, and cellular metabolism, providing insights into the therapeutic potential of targeting SIRT2.
Product Information
Catalog NumA57018
FormulaC26H21N3O4
Molecular Weight439.46
CAS Number1884571-59-8
SMILESO=C(NC1=CC=CC(COC2=CN=CC(C(N)=O)=C2)=C1)C(C=C3)=CC=C3OC4=CC=CC=C4
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