Sirt2-IN-5

Catalog No.: A56998
SIRT2 Inhibtor
Sirt2-IN-5 is a selective inhibitor of SIRT2, a member of the sirtuin family involved in various cellular processes, including metabolism and stress response. This compound effectively reduces SIRT2 activity, thus influencing downstream signaling pathways associated with neuroprotection and cancer biology. It is useful in research applications focusing on the roles of SIRT2 in disease models and exploring therapeutic strategies targeting sirtuins.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSirt2-IN-5 is a selective inhibitor of SIRT2, a member of the sirtuin family involved in various cellular processes, including metabolism and stress response. This compound effectively reduces SIRT2 activity, thus influencing downstream signaling pathways associated with neuroprotection and cancer biology. It is useful in research applications focusing on the roles of SIRT2 in disease models and exploring therapeutic strategies targeting sirtuins.
Product Information
Catalog NumA56998
FormulaC26H27Cl2N5O3
Molecular Weight528.43
CAS Number902456-47-7
SMILESO=C1C(C2=CC=C(Cl)C=C2)=CC(N3CCOCC3)=NN1CC(N4CCN(C5=CC=CC(Cl)=C5)CC4)=O
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